Mediterranean diet and tirzepatide: the ideal combination

The Mediterranean diet represents the most well-documented dietary approach to complement tirzepatide treatment. Rich in anti-inflammatory foods and low in ultra-processed products, it optimizes the metabolic results of the treatment. Why the Mediterranean diet is ideal with tirzepatide The Mediterranean diet has been recognized by the WHO and the World Obesity Federation as the … Read more

Gastroparesis under GLP-1 Agonists: Symptoms and Prevention

Gastroparesis is a rare but potentially debilitating side effect of GLP-1 agonists. Here’s how to recognize and prevent it. Gastroparesis, defined by an abnormal slowing of gastric emptying without mechanical obstruction, has received considerable media attention with the rise of GLP-1 treatments. Although rare, this complication can be debilitating and … Read more

Mounjaro and Heart Failure: The SUMMIT Study

The SUMMIT study demonstrates that tirzepatide significantly improves symptoms and prognosis of heart failure in obese patients. Heart failure with preserved ejection fraction (HFpEF) is one of the most frequent and challenging forms of heart failure to treat, particularly affecting obese patients. The SUMMIT study, published in the New England … Read more

Tirzepatide in Obese Adolescents: The SURMOUNT-Jr Study

The SURMOUNT-Jr study paves the way for the treatment of severe obesity in adolescents with tirzepatide, showing superior results to any existing treatment. Pediatric obesity is a global public health crisis. In France, approximately 18% of children and adolescents are overweight or obese, with major physical and psychological consequences. The SURMOUNT-Jr study, … Read more

Weight Regain After Tirzepatide Discontinuation: What Do the Data Say?

Discontinuing tirzepatide leads to weight regain in the majority of patients. Here are the scientific data and strategies to limit this phenomenon. One of the most important questions for patients on Mounjaro is: what happens when treatment is stopped? Data from the SURMOUNT-4 study and observational studies provide … Read more

Tirzepatide and Fatty Liver Disease (NASH): Promising Results

Tirzepatide could become the first effective drug treatment for non-alcoholic steatohepatitis (NASH), a disease affecting millions of French people. Non-alcoholic fatty liver disease (NAFLD), and its progressive form, steatohepatitis (NASH), represent one of the greatest silent epidemics of the 21st century. In France, it is estimated that 18 to 25% of … Read more

Mounjaro and Sleep Apnea: Results of the SURMOUNT-OSA Study

The SURMOUNT-OSA study demonstrates that tirzepatide significantly reduces the severity of obstructive sleep apnea, offering an alternative to mechanical treatments. Obstructive sleep apnea (OSA) affects approximately 30 to 40% of obese individuals. This condition, characterized by repeated interruptions of breathing during sleep, increases cardiovascular risk and significantly deteriorates … Read more

SURPASS-CVOT: Does Mounjaro Reduce Cardiovascular Risk?

The SURPASS-CVOT study is the largest cardiovascular trial ever conducted with tirzepatide. Its results could transform treatment recommendations. The question of cardiovascular safety for anti-obesity treatments is fundamental. The SURPASS-CVOT (Cardiovascular Outcomes Trial) study was designed to evaluate whether tirzepatide (Mounjaro) reduces the risk of major cardiovascular events in patients … Read more