The SURMOUNT-2 study demonstrates that tirzepatide is equally effective in patients combining type 2 diabetes and obesity, with major glycemic benefits. Following the spectacular results of SURMOUNT-1 in non-diabetic patients, the question arose: would tirzepatide be as effective in patients simultaneously presenting with type 2 diabetes … Read more
The SURMOUNT-1 study laid the scientific foundation for the use of tirzepatide in obesity. A detailed analysis of the game-changing results. Published in the New England Journal of Medicine in July 2022, the SURMOUNT-1 study is the pivotal clinical trial that led to the authorization of tirzepatide (Zepbound) for the treatment of obesity. With 2,539 participants … Read more
Survodutide, retatrutide, orforglipron: molecules that could surpass Mounjaro are already in advanced clinical trials. While tirzepatide (Mounjaro/Zepbound) has revolutionized obesity treatment with its dual GIP/GLP-1 action, pharmaceutical research doesn’t stop. Several new-generation molecules are under development, promising even more impressive results. An overview of treatments that could redefine obesity management in the coming years. Read more
Tirzepatide does more than just reduce appetite: it simultaneously acts on three vital organs to combat obesity and type 2 diabetes. Tirzepatide, the active ingredient in Mounjaro and Zepbound, is often presented as a simple injectable appetite suppressant. This reductive view ignores the complexity of its mechanism of action. In reality, this … Read more
From Mediator to Fen-Phen and rimonabant: the history of anti-obesity treatments and why GLP-1s represent a revolution.
A comprehensive overview of GLP-1 agonists available in France in 2026: Mounjaro, Ozempic, Wegovy, Trulicity. Comparison, reimbursement, and future molecules.
GIP receptors are the key differentiating factor for Mounjaro. Their role in adipose tissue, the brain, and bones explains the superiority of tirzepatide.
Tirzepatide Half-Life: How 3 Chemical Modifications Transform a 3-Minute Hormone into a Weekly Treatment. Pharmacokinetics Explained.
How tirzepatide reduces appetite: mechanisms of satiety, food noise, neuronal signals. What patients experience and how to optimize.
Zepbound and Mounjaro contain the same tirzepatide. What are the differences? Indications, reimbursement, availability in France. All you need to know in 2026.
Mounjaro vs Wegovy: complete 2026 comparison. Weight loss, side effects, cardiovascular benefits, cost. Which one to choose based on your profile?
Mounjaro vs Ozempic: A comprehensive comparison of the two GLP-1 treatments. Efficacy, side effects, price, and selection criteria based on clinical studies.